We are pleased beyond measure to have successfully renewed our Retinal Remodeling R01, and look forward to a continued process of discovery in retinal plasticity of visually degenerate retina, this time with a connectomics angle.
Bryan W. Jones and Robert E. Marc and were selected as
2013 FASEB BioArt Winners ( Press release here). This image shows a region of an amazingly complex retina from a goldfish ( ) analyzed using tools called Carassius auratus auratus Computational Molecular Phenotyping (CMP) that reveal the metabolic state of the all cell types in tissues. These cells were labeled with antibodies for the presence of two fundamental amino acid metabolites ( anti-glycine in red, anti-GABA in blue) and an amino acid tracer of physiologic activity ( anti-AGB in green). These labels allow us to visualize the metabolic state and therefore, classes of bipolar, amacrine and horizontal cells. More details on the image here.
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Awards and tagged 1-amino-4-guanidobutane, AGB, BioArt, Bryan Jones, Bryan William Jones, BWJones, FASEB, GABA, glycine, NEI, NIH, retina, Robert Marc on September 11, 2013 by . bwjones