Carl B. Watt

Carl B. Watt, Ph.D. – SELECTED PUBLICATIONS

2000-2019

Jones BW, Pfeiffer RL, Ferrell WD, Watt CB, Tucker J, Marc RE. 2016
Retinal Remodeling and Metabolic Alterations in Human AMD
Front Cell Neurosci. Apr 28;10:103
PubMed PMID 27199657 PubMedCentral PMCID PMC4848316

Jones BW, Pfeiffer RL, Ferrell WD, Watt CB, Marmor M, Marc RE 2016
Retinal remodeling in human retinitis pigmentosa
Exp Eye Res. Sep;150:149-65
PubMed PMID 27020758 

Marc RE, Anderson JR, Jones BW, Sigulinsky C, Watt CB, Lauritzen JS 2015
High-resolution synaptic connectomics.
In New Techniques in Systems Neuroscience Springer. Douglass, Adam (Ed.)

Marc RE, Anderson JR, Jones BW, Sigulinsky C, Watt CB, Lauritzen JS 2014
The AII amacrine cell connectome: a dense network hub.
Front. Neural Circuits, 04 September 2014 | doi: 10.3389/fncir.2014.00104.
PubMed PMID 25237297 PubMedCentral PMCID PMC4154443

Marc RE, Anderson JR, Jones BW, Watt CB, Lauritzen JS 2013
Retinal Connectomics: Towards Complete, Accurate Networks
Prog Ret Eye Res, in press ∞ PDF

Lauritzen JS, Anderson JR, Jones BW, Watt CB, Mohammed S, Hoang JV, Marc RE 2012
ON cone bipolar cell axonal synapses in the OFF inner plexiform layer of the rabbit retina.
J Comp Neurol 521:977-1000 doi: 10.1002/cne.23244. [epub ahead of print]
PubMed PMID 23042441

Marc RE, Jones BW, Lauritzen JS, Watt CB, Anderson JR. 2013
Retinal Connectomics: A new era for connectivity analysis.
New Visual Neurosciences. In Press.

Marc RE, Anderson JR, Jones BW, Watt CB 2012
Building retinal connectomes.
Current Opinion in Neurobiology 22:568-574. :: PubMed PMID 22498714::

Lin Y, Jones BW, Liu A, Tucker JF, Rapp K, Luo L, Baehr W, Bernstein PS, Watt CB,Yang J-H, Shaw MV, Marc RE. 2011 Retinoid receptors trigger neuritogenesis in retinal degenerations. The FASEB Journal 26: 81-92. PubMed PMID 21940995:: PubMedCentral PMC3250249::

Jones A, Kumar S, Zhang N, Tong Z, Yang JH, Watt C, Anderson J, Amrita, Fillerup H, McCloskey M, Luo L, Yang Z, Ambati B, Marc R, Oka C, Zhang K, Fu Y 2011 Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice. Proc Natl Acad Sci U S A. 108:14578-83. Epub 2011 Aug 15 :: PubMed PMID 21844367:: PubMedCentral PMC3167497::

Jones BW, Kondo M, Terasaki H, Watt CB, Rapp K, Anderson J, Lin Y, Shaw MV, Yang J-H, Marc R2011 Retinal Remodeling in the Tg P347L Rabbit, a Large-Eye Model of Retinal Degeneration. J Comp Neurol. 2011 1;519(14):2713-2733 :: PubMed PMID 21681749::

Anderson JR, Jones BW, Watt CB, Shaw MV, Yang J.-H., DeMill D, Lauritzen J.S., Lin Y., Rapp KD, Mastronarde D, Koshevoy P, Grimm B, Tasdizen T, Whitaker R, Marc RE 2011 Exploring the retinal connectome. ∞ Molecular Vision 17:355-379 :: PubMed PMID 21311605:: ∞ PDF

Anderson JR, Jones BW, Yang J-H, Shaw MV, Watt CB, Koshevoy P, Spaltenstein J, Jurrus E, Kannan UV, Whitaker R, Mastronarde D, Tasdizen T, Marc R 2009 A computational framework for ultrastructural mapping of neural circuitry. PLoS Biol 7(3): e1000074 [doi:10.1371/journal.pbio.1000074]
PubMed PMID 19855814:: PubMedCentral PMC2661966

Avasthi P, Watt CB, Williams DS, Le YZ, Li S, Chen CK, Marc RE, Frederick JM, Baehr W. 2009Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II. J Neurosci. 2009 Nov 11;29(45):14287-98.
PubMed PMID 19906976 PubMedCentral PMC 2788486

Marc RE, Jones BW, Watt CB, Vazquez-Chona F, Vaughan DK, Organisciak DT 2008 Extreme retinal remodeling triggered by light damage: Implications for AMD. Molecular Vision 14:782-806.PubMed PMID 18483561 :: PubMedCentral PMC 2375357

Jones BW, RE Marc, CB Watt, DK Vaughan, DT Organisciak 2006 Neural plasticity revealed by light-induced photoreceptor lesions. Retinal Degenerative Diseases, Springer, (New York), pp. 405-410.

Jones BW, CB Watt and RE Marc. 2005 Retinal remodeling in retinal degenerations. Clinical and Experimental Optometry 88: 282-291. PubMed PDF

Marc RE, BW Jones and CB Watt 2005 Retinal remodeling: Circuitry revisions triggered by photoreceptor degeneration. In Plasticity in the Visual system: from Genes to Circuits. Eds, Pinaud et al., Springer, pp. 33-54.

Marc RE, BW Jones, CB Watt and E Strettoi 2003 Neural Remodeling in Retinal Degeneration. Progress in Retinal and Eye Research 22: 607-655. PubMed PDF

Jones BW, CB Watt, JM Frederick, W Baehr, CK Chen, EM Levine, AH Milam, MM LaVail, RE Marc 2003 Retinal remodeling triggered by photoreceptor degenerations. J Comp Neurol 464: 1-16.PubMed PDF


1990-1999

  • Li, T., S.M. Wu, D.M.K. Lam and C.B. Watt (1990) Localization of classical transmitters in interneurons of the larval tiger salamander retina. Invest. Ophthalmol. Vis. Sci., 31:262-271.
  • Watt, C.B. and E.A. Wilson (1990) Synaptic organization of serotonin-like immunoreactive amacrine cells in the larval tiger salamander retina. Neurosci. 35:715-723.
  • Li, H.B., C.B. Watt and D.M.K. Lam (1990) Double-label analyses of somatostatin’s coexistence with enkephalin and gamma-aminobutyric acid in amacrine cells of the chicken retina. Brain Res. 525:304-309.
  • Fry, K.R., D.M. Edwards, K.A. Shaw and C.B. Watt (1991) The rabbit retina: a long-term model system for aluminum-induced neurofibrillary degeneration. Neurosci. Lett., 124:216-220.
  • Watt, C.B. (1991) A re-examination of enkephalin’s coexistence with gamma-aminobutyric acid in amacrine cells of the larval tiger salamander retina. Brain Res., 551:351-354.
  • Watt, C.B., P.A. Glazebrook and H.B. Li (1991) Coexistence of somatostatin and neurotensin in amacrine cells of the chicken retina. Brain Res., 546:166-170.
  • Watt, C.B. and V.J. Florack (1991) Double-label analysis demonstrating the non-coexistence of enkephalin and glycine in amacrine cells of the larval tiger salamander retina. Brain Res., 562:154-158.
  • Watt, C.B. (1991) A double-label analysis demonstrating that all enkephalin-like immunoreactive amacrine cells in the chicken retina express neurotensin immunoreactivity. Brain Res., 566:337-341.
  • Watt, C.B. and V.J. Florack (1991) A double-label study demonstrating that enkephalin and somatostatin are localized in separate populations of amacrine cells in the larval tiger salamander retina. Neurosci. Lett., 133:86-88.
  • Watt, C.B. (1992) A double-label study demonstrating that all serotonin-like immunoreactive amarcine cells in the larval tiger salamander retina express GABA-like immunoreactivity. Brain Res., 583:336-339.
  • Watt, C.B. (1992) Double-label analysis demonstrating the non-coexistence of tyrosine-like and GABA-like immunoreactivities in amacrine cells of the larval tiger salamander retina. Neurosci. Lett., 148:47-50.
  • Watt, C.B. and P.A Glazebrook (1993) The synaptic organization of dopaminergic amacrine cells in the larval tiger salamander retina. Neurosci., 53:527-536.
  • Watt, C.B., V.J. Florack and R.B. Walker (1993) Quantitative analyses of the coexistence of GABA in substance P-amacrine cells of the larval tiger salamander retina. Brain Res., 603:111-116.
  • Watt, C.B. and V.J. Florack (1993a) Double-label analyses of th coexistence of somatostatin with GABA and glycine in amacrine cells of the larval tiger salamander retina. Brain Res., 617:131-137.
  • Watt, C.B. and V.J. Florack (1993b) Colocalization of glycine in substance P-amacrine cells of the larval tiger salamander retina. Vis. Neurosci., 10:899-906.
  • Watt, C.B. and V.J. Florack (1993c) Colocalization between enkephalin and glycine in amacrine cells of the chicken retina. Brain Res., 628:349-355.
  • Watt, C.B. and V.J. Florack (1994a) A triple-label analysis demonstrating that enkephalin-, somatostatin- and neurotensin-like immunoreactivities are expressed by a single population of amacrine cells in the chicken retina. Brain Res., 634:310-316.
  • Watt, C.B. and V.J. Florack (1994b) Interaction between enkephalin and GABA in the chicken retina. Brain Res., 634:317-324.
  • Watt, C.B., P.A. Glazebrook and V.J. Florack (1994) Localization of substance P and GABA in retinotectal ganglion cells of the larval tiger salamander. Vis. Neurosci., 11:355-362.
  • Watt CB, PA Glazebrook 1994 Interaction between enkephalin and GABA in the chicken retina: A double-label immunoelectron microscopic analysis. J Comp Neurol 342: 378-388.

1980-1989

  • Mihailoff, G.A., C.B. Watt and R.A. Burne (1981) Evidence demonstrating that both the corticopontine and cerebellopontine systems are each composed of two separate neuronal elements: An electron microscopic and horseradish peroxidase study in the rat. J. Comp. Neurol. 195:221-242.
  • Mihailoff, G.A. and C.B. Watt (1981) Cerebral cortical afferent terminations on identified spiny basilar pontine neurons: A combined Golgi-EM degeneration study. Brain Res. Bull. 6:227-234.
  • Watt, C.B. and G.A. Mihailoff (1983) Electron microscopic identification of superior colliculo-pontine axon terminals. Neuroscience Letters. 35:7-13.
  • Watt, C.B. and G.A. Mihailoff (1983) The cerebellopontine system in the rat. I. Autoradiographic studies. J. Comp. Neurol. 215:312-320.
  • Watt, C.B. and G.A. Mihailoff (1983) The cerebellopontine system in the rat. II. Electron microscopic studies. J. Comp. Neurol. 216:429-437.
  • Watt, C.B., Y.Y.T. Su and D.M.K. Lam (1984) Interactions between enkephalin and GABA in an avian retina: Physiological studies and simultaneous visualization of putative GABAergic and enkephalinergic neurones. Nature, 311:761-763.
  • Watt, C.B., Y.Y.T. Su and D.M.K. Lam (1985) Opioid pathways in an avian retina: 2. The synaptic organization of enkephalin immunoreactive amacrine cells. J. Neurosci., 5:857-865.
  • Su, Y.Y.T., C.B. Watt and D.M.K. Lam (1985) Opioid pathways in an avian retina: 1. Biosynthesis and release of enkephalin in the chicken retina. J. Neurosci., 5:851-856.
  • Tavella, D., C.B. Watt, Y.Y.T. Su, K.-J. Chang, S. Handlin, V. Gaskie and D.M.K. Lam (1985) The production and characterization of monoclonal antibodies against enkephalins. Neurochem. Internatl., p. 455-466.
  • Fry, K.R., D. Tavella, Y.Y.T. Su, Y.-W. Peng, C.B. Watt, S. Handlin, V. Gaskie and D.M.K. Lam (1985) A monoclonal antibody specific for retinal ganglion cells of higher mammals. Brain Res., 338:360-365.
  • Li, H.B., C.B. Watt and D.M.K. Lam (1985) The coexistence of two neuroactive peptides in a subpopulation of retinal amacrine cells. Brain Res., 345:176-180.
  • Watt, C.B., H.B. Li, K.R. Fry and D.M.K. Lam (1985) Localization of enkephalin-like immunoreactive amacrine cells in the larval tiger salamander retina: A light and electron microscopic study. J. Comp. Neurol., 241:171-179.
  • Watt, C.B., H.B. Li and D.M.K. Lam (1985) The presence of three neuroactive peptides in glycinergic amacrine cells of an avian retina. Brain Res., 348:187-191.
  • Lam, D.M.K., H.B. Li, Y.Y.T. Su and C.B. Watt (1985) The signature hypothesis: Co-localizations of neuroactive substances as anatomical probes for circuitry analyses. Vis. Res. 25:1353-1364.
  • Mihailoff, G.A., H. Lee, C.B. Watt and R. Yates (1985) Projections to the basilar pontine nuclei from face sensory and motor regions of the cerebral cortex in the rat. J. Comp. Neurol. 237:251-263.
  • Li, H.B., N.X. Chen, C.B. Watt and D.M.K. Lam (1986) The light microscopic localization of substance P- and somatostatin-like immunoreactive cells in the larval tiger salamander retina. Exp. Brain Res., 63:93-101.
  • Lam, D.M.K., Y.Y.T. Su and C.B. Watt (1986) The self-regulating synapse: A functional role for the coexistence of neuroactive substances. Brain Res. Rev. 11:249-257.
  • Su, Y.Y.T., K.R. Fry, D.M.K. Lam and C.B. Watt (1986) Enkephalins in the goldfish retina. Cell and Molec. Neurobiol. 6:1-20.
  • Watt, C.B., T. Li, D.M.K. Lam and S.M. Wu (1987) Interactions between enkephalin and gamma-aminobutyric acid in the larval tiger salamander retina. Brain Res. 408:258-262.
  • Su, Y.Y.T. and C.B. Watt (1987) Interaction between enkephalin and dopamine in the avian retina. Brain Res. 423:63-70.
  • Yu, B.Y., C.B. Watt, D.M.K. Lam and K.R. Fry (1987) GABAergic ganglion cells in the rabbit retina. Brain Res. 439:376-382.
  • Yang, S.Z., C.B. Watt, D.M.K. Lam and S.M. Wu (1988) Localization of neurotensin-like immunoreactive amacrine cells in the larval tiger salamander retina. Exp. Brain Res., 70:33-42.
  • Watt, C.B., T. Li, D.M.K. Lam and S.M. Wu (1988) Quantitative studies of enkephalin’s coexistence with gamma-aminobutyric acid, glycine and neurotensin in amacrine cells of the chicken retina. Brain Res., 444:366-370.
  • Watt, C.B., S.Z. Yang, D.M.K. Lam and S.M. Wu (1988) Localization of tyrosine hydroxylase-like immunoreactive amacrine cells in the larval tiger salamander retina. J. of Comp. Neurol., 272:114-126.
  • Watt, C.B. (1989) Synaptic organization of enkephalin-like immunoreactive amacrine cells in the goldfish retina. J. Comp. Neurol., 283:333-341.
  • Yang, S.Z., D.M.K. Lam and C.B. Watt (1989) Localization of serotonin-like immunoreactive amacrine cells in the larval tiger salamander retina. J. Comp. Neurol., 287:28-37.