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Robert E. Marc :: 2016 Harvard AMD Conference Presentation :: marc-2016-harvard 141 Mb PDF

Connectomics for K-12
Brains in Cinema
Connectomics & Eternity
Marclab Journal Cover Gallery

Eye Candy Gallery
RC1 Connectome Navigation Movie (right-click or control-click and download)(self-playing moving)
Play or Download 33 MB.mov
Connectomics Summary Movie (right-click or control-click and download)(self-playing moving)
Play or Download 79 MB.mov

Connectomics Summary Gallery
Marc 2012-07-Senses-vision flat lg.pdf (right-click or control-click and download)
Download 11 MB PDF
IMAGE :: Journal of Microscopy Fig 11 300dpi 51 picas w X 46 picas h LZW compressed Download 9MB jpg.

Caption: A keyframe image for a 90 section subvolume of retinal connectome RC1. RC1 is composed of over 340,000 transmission electron microscope (TEM) images from 341 sections spanning a 250 μm diameter tissue column, assembled into single analysis volume parsed by the Viking application. The subvolume, 17.8 μm wide with a native resolution of 2.18 nm/pixel, was designed as a public test volume for tracking algorithms. The six colored processes have different topologies that vary in tracking difficulty: yellow > green > red > lavender > blue > cyan.

 REM Presentation at Photocamp Utah 2010 lecture MP4 (right-click or control-click and download)
Download MP4 (223 MB)
© REMarc 2010
IMAGE Connectome large (right-click or control-click and download)
Download jpg as 23 MB
© REMarc 2010
PRESENTATION Marc 114th Japanese Society for Ophthalmology lecture 2010 lecture (right-click or control-click and download)
Download pdf
© REMarc 2010
gallery2_20_senses_iconPRESENTATION Ignite SL 2.0 :: The Twenty Senses (right-click or control-click to download, left click to play)Med MOV version: 6 Mb 512 x 384 px, 12 FPS Ignite 20 Senses © REMarc 2009 Self playing, about 10 sec/frame. Youtube of presentation at Ignite SL 2.0 here.
Remodeling animation mp4: This animation is a morph of three separate datasets spanning about 2 years in the life of a “GHL” mouse that expresses a transgenic mutant of rhodopsin on a normal rhodopsin background. The GHL rhodopsin slowly kills the rods over about a year – halfway thru the animation – it is a model of human autosomal dominant RP. After rod death, three major events transform the neural retina: (1) slow neuronal death; (2) glial and neuronal migration; (3) rewiring (not directly visible in this scheme). The colors represent mixtures of signature molecules that allows tracking key cell classes (taurine=RED, glutamine=green, glutamate=blue). Müller cells have a characteristic yellowish signature in this representation. The animation also shows the well-known invasion of the retina by the RPE (golden brown cell mass).Animation by Dr. Bryan William Jones.
© BWJones 2003
IMAGE Remodeling diagrams: A set of static remodeling diagrams (*.tif) at full (1024 x 768) Keynote or Powerpoint resolution with LZW compression. All at 250-500 Kb and each has descriptive text.

Normal → Phase 1 Remodeling Diagram (right-click or control-click and download)

Normal → Phase 1 Remodeling Diagram text (right-click or control-click and download)
Phase 1 → Phase 2 Remodeling Diagram (right-click or control-click and download)
Phase 2 → Early Phase 3 Remodeling Diagram (right-click or control-click and download)
Early Phase 3 → Late Phase 3 Remodeling Diagram (right-click or control-click and download)

© REM 2004

Microneuromas (right-click or control-click and download)
Microneuromas: An image of GABA signals showing extensive microneuroma formation in the hrhoG degeneration model (*.tif) at full (1024 x 768) Keynote or Powerpoint resolution with LZW compression. Microneuromas are rewiring tufts of varying size: as small as 10 µm to over 200 µm. They are not visible in normal histological preps but with hi res, hi def immunocytochem, they are clearly profuse. In some rodents they are present at 10,000-30,000 / retina. That only includes the larger, more obvious ones. The double circled tuft is actually in the RPE layer, outside the retina.© REM 2005
Human_remodeling (right-click or control-click and download)
Advanced remodeling in the human retina: A fully labeled multispectral image (taurine=red, glycine=green, glutathione=blue) of human RP retina in advanced stages – the patient had been completely blind for decades. Full (1024 x 768) Keynote or Powerpoint resolution with LZW compression. This tissue bears no resemblance to retina nand was drawn from a dataset spanning 19 mm of retina. All was of similar disorganization.© REM 2005