IAC 9769 is a wide-field pure feedforward GABAergic interstitial amacrine cell (IAC). This is the first pure feedforward GABAergic AC discovered. IAC 9769.

• collects excitation exclusively from ON (CBb) bipolar cells (BCs)
• provides inhibitory feedforward different of ON ganglion cell (GC) classes
• engages in nested feedforward to other classes of GABAergic ACs
• is coupled to different classes of GABA+ GCs (e.g. GC 606 at 2 sites)
• is coupled tip-to-tip to other ACs resembling IACs.

Images of 9769

IAC 9769 and GC 606
Legend
Red IAC 9769. Blue GC 606. Gold dots = gap junctions. Arrow = fasciculation.

*.svg files for visualization

9769 1-hop reduced-edge network

9769 2-hop reduced-edge network

9769 3-hop reduced-edge network

GraphViz *.dot files for import into GraphViz-compliant viewers

9769 1-hop reduced-edge network *.dot file

9769 2-hop reduced-edge network *.dot file

9769 3-hop reduced-edge network *.dot file

A_II AC 476 is a narrow-field rod BC-driven glycinergic amacrine cell (AC). A_II ACs are the fundamental rod → cone crossover elements of the retina A_II ACs

• collect excitation from rod BCs
• are coupled to all CBb cells
• are presynaptic and postsynaptic to all CBa cells
• are heavily coupled in an A_II :: A_II network
• provide crossover feedforward inhibition to ON α and δ GCs
• are postsynaptic to many GABA+ AC classes
• are presynaptic to specific OFF GABA+ ACs that engage in cone → rod crossover

Images of 476

ACs 514, 476, 410, 2610
Legend
Four rendered A_II ACs superimposed on RC1 slice 001. Also shown are numerous other A_II ACs located at their XY positions in the volume. Most are not visible in Slice 001, being positioned deeper in the volume.

*.svg files for visualization

476 1-hop reduced-edge network

476 2-hop reduced-edge network

476 3-hop reduced-edge network

GraphViz *.dot files for import into GraphViz-compliant viewers

476 1-hop reduced-edge network *.dot file

476 2-hop reduced-edge network *.dot file

476 3-hop reduced-edge network *.dot file