Tag Archives: Beth Coughlin

The Alternative Complement Pathway Deficiency Amerliorates Chronic Smoked-Induced Functional And Morphological Ocular Injury

Alex Woodell, Beth Coughlin, Kannan Kunchithapautham, Sarah Casey, Tucker Williamson, W. Drew Ferrell,  Carl Atkinson, Bryan Jones and Baerbel Rohrer have a new manuscript out, The Alternative Complement Pathway Deficiency Amerliorates Chronic Smoked-Induced Functional And Morphological Ocular Injury in PLOS One.

The short story is: Don’t smoke.  But then you knew that.  Where this paper contributes is that it provides clear findings that show ocular pathologies generated by cigarette smoke are dependent upon activation of the immune system, in particular complement and the alternative pathway which are critical findings in the treatment of AMD.